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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: The let-7 family of microRNAs suppresses immune evasion in head and neck squamous cell carcinoma by promoting PD-L1 degradation

Fig. 6

Over-expressed let-7 suppresses the TCF-4 expression in HNSCC. a the TCF-4 expression (× 400) in HNSCC tissues and adjacent normal tissues examined by immunohistochemistry. b and c the correlation between let-7a/7b and TCF-4 by western blot analysis and RT-qPCR. * p < 0.05 compared with the control group. The results were measurement data and were expressed as mean ± standard deviation. Data between two groups were analyzed by paired t test. Each experiment was run in triplicate. N = 37. TCF-4, transcription factor 4; HNSCC, squamous cell carcinoma of the head and neck; TR-qPCR, reverse transcription quantitative polymerase chain reaction

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