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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients

Fig. 7

Increased levels of GREM1 mRNA are associated with lack of estrogen receptor expression. Level of GREM1 transcript in 60 different human breast cancer cell lines analyzed using the Cancer Cell Line Encyclopedia made available by Broad Institute. (a) GREM1 transcript levels were elevated in some cell lines, but this did not correlate with GREM1 copy number variations. (b) Correlation of the GREM1 and estrogen receptor (ERS1) transcript levels. Transcript levels were determined using RNA-sequencing and compared to the average expression in more than 1000 human cancer cell lines for each transcript

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Cell Communication and Signaling

ISSN: 1478-811X