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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling

Fig. 2

Expression of EMT markers in breast cancer cells and clinical samples. a Expression of EMT markers in two normal breast cell lines, eight luminal, and seven BLBC cell lines by western blot (S: Short exposure; L: Long exposure). b Expression of selected EMT marker mRNAs in basal-like specific based on bc-GenExMiner v4.1 according to the Sørlie’s subtypes (***p < 0.001; ****p < 0.0001; Red star: the former > the latter; Green Star: the former < the latter). c Expression of selected EMT marker mRNAs in TNBC-specific based on UALCAN (Red p: the former > the latter; Green p: the former < the latter). d Expression of E-cadherin and vimentin in representative Her-2 positive, luminal A, luminal B and basal-like breast cancer tissues by IHC (Red scale bar = 200 μm; Purple scale bar = 40 μm). e The association of E-cadherin or vimentin expression between basal-like and non-BLBC tissue subtypes were assessed using Pearson’s χ2 test (for E-cadherin, p < 0.0001, basal-like < non-basal-like; for vimentin, p < 0.0001, basal-like > non-basal-like)

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