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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Exosomes released from neural progenitor cells and induced neural progenitor cells regulate neurogenesis through miR-21a

Fig. 2

EXOs and iEXOs exhibit distinct miRNA profiles. (a) The miRNAs profiles of iEXOs and EXOs are represented in the heat map and hierarchical clustering-based dendrograms. (b) The volcano plot shows the relation between the logarithm of the p-values and the log fold change. (c) The differentially expressed miRNAs between iEXOs and EXOs are represented in the heat map and hierarchical clustering-based dendrograms. (d) The microarray data were validated by examining the expression patterns of randomly selected miRNAs using qPCR. (e) The intracellular expression levels of differentially expressed miRNAs in iNPCs and NPCs were determined by qPCR analysis and represented in the heat map. Data were represented as mean ± SD from three independent experiments. *** and **** denote p < 0.001 and p < 0.0001, respectively. n.s. denotes no significance

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Cell Communication and Signaling

ISSN: 1478-811X