Fig. 7
From: Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells
Osteoblastic differentiation of Human Gingival Mesenchymal Stem Cells associates with modulation of the AMPK-BECLIN-1 autophagy signaling pathway. HGMSCs were cultured for 1 to 21 days in control medium or in differentiation medium (Diff) supplemented or not with 1 μM resveratrol (RV). At the end, cell homogenates were processed for western blotting analysis of the expression of activated (phosphorylated) AMPK and BECLIN-1, two signaling proteins that govern autophagy. Densitometry (arbitrary units) is included. Similar data were reproduced in another independent experiment