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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Wnt signaling: a promising target for osteoarthritis therapy

Fig. 5

Interaction within TGF-b/BMP, canonical and non-canonical signaling pathway in osteoblast, in addition to induces DKK2 to inhibit the canonical Wnt signaling pathway, TGF-b/BMP signaling also up-regulates the expression of Wnt5a In osteoblasts, and subsequently stimulating the expression of a number of genes involved with osteogenesis

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