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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213

Fig. 6

Phosphorylation of AR Ser 213 and AKT signaling pathway were suppressed by CAPE treatment. Cells treated with CAPE and DHT for 48 h were harvested for Western blotting analysis. The expression level of phospho-AR Ser213, AKT, phospho-AKT T308 and phospho-AKT S473 were determined in LNCaP 104-S cells (a) and LNCaP 104-R1 cells (b). LNCaP 104-S (c) and LNCaP 104-R1 (d) cells overexpressing AKT were treated with CAPE and DHT for 48 h and collected lysates to analyze protein expression of AR and CDK1. β-actin was used as loading control

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Cell Communication and Signaling

ISSN: 1478-811X