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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer

Fig. 1

Leucine transport is regulated by PI3K/Akt signalling. a and b, leucine transport was examined in the presence of LY294002, MK2206, BCH and JPH203 in LNCaP (a) and PC-3 cells (b). One-way ANOVA was performed. Data are the mean ± SEM, n = 4. c and d, Akt activation was examined in the presence of LY294002, MK2206, BCH or JPH203 in LNCaP (c) and PC-3 cells (d) by western blot. GAPDH was used as the loading control. The densitometry of pAkt was normalised to Akt. All western blot images are representative of three independent experiments

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