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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: miR-449a regulates insulin signalling by targeting the Notch ligand, Jag1 in skeletal muscle cells

Fig. 1

Target prediction of miR-449a. a Predicted miR-449a targets were extracted from miRanda, miRDB and TargetScan, and a list of 217 genes was identified as the common target set. b Pathway analyses of the- common predicted targets showed Notch signalling as one of the most significant over-represented pathway. The figure represents the combined scores (obtained from ENRICHR) of the pathways listed. c miR-449a harbors a binding site on the Jag1 3′UTR that spans across 1333–1354 nucleotides and this is conserved across several species (d)

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