Fig. 6
From: YAP promotes neural crest emigration through interactions with BMP and Wnt activities
YAP signaling is required for BMP activity. Transverse sections of embryos co-electroporated with the BMP reporter BRE-GFP (green) and either a control scrambled RNA (a-a”), or shYAP (b-b″). Note the presence of double positive cells in controls (arrows in a”) and of mostly shYAP+/BRE-negative progenitors in the dorsal NT of shYAP-treated embryos (arrowheads in b″). (c) Left and right graphs show quantification of the percentage of double labeled progenitors out of total RFP+ cells in premigratory (*p < 0.001) and emigrating (**p < 0.0005) NC cells, respectively. (d) Left and right graphs show quantification of the percentage of double labeled progenitors out of total RFP+ cells in premigratory and emigrating NC cells, respectively. (*p < 0.004, **p < 0.0001, ***p < 0.00001). Bar = 50 μM