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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Connexin30 and Connexin43 show a time-of-day dependent expression in the mouse suprachiasmatic nucleus and modulate rhythmic locomotor activity in the context of chronodisruption

Fig. 1

Relative expression profile of Cx30 and Cx43 mRNA levels under different light regimes. Relative Cx30 (a) and Cx43 (b) mRNA expression levels in the SCN of C57Bl/6 mice at six different time points in 12:12 LD. White bars show light phase, black bars show dark phase. Relative Cx30 (c) and Cx43 (d) mRNA expression levels in the SCN of C57Bl/6 mice at six different time points in constant darkness. Grey bars show former light phase, black bars show former dark phase. Relative Cx30 (e) and Cx43 (f) mRNA expression levels to RN18S in the SCN of C57Bl/6 mice at six different time points in constant light. Data are expressed as mean +/− SEM of n = 3 mice per time point. Significant differences among different time points were analysed by one way ANOVA followed by Tukey’s posthoc test. Both, Cx30 (F = 10.1; P = 0.0006) and Cx43 (F = 4.24; P = 0.02) mRNA levels were significantly different among different time points under 12:12 LD conditions. *:p ≤ 0.05 vs. ZT22, ***:p ≤ 0.001 vs. ZT22. There were no significant differences in Cx30 or Cx43 mRNA levels among different time points under DD or LL conditions

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