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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer

Fig. 8

GFPT2 expression correlates with poor clinical outcomes. a Kaplan-Meier analysis using LUAD patients with elevated GFPT2 mRNA expression show decreased 5-year survival rates, compared GFPT1 expression which failed to correlate with clinical outcomes. High GFPT2 expression (> 9 RNA Seq V2 RSEM) verses low (< 6 RNA Seq V2 RSEM); n = 517. Median month survival for patients with high GFPT2 expression 37.68, compared to low GFPT2 expression 53.61 months. b Representative immunohistochemistry images of human lung cancer tissue microarrays stained for GFPT2 expression in malignant lung cancer, compared to adjacent benign lung. The percent of malignant lung cancer that stained positive of GFPT2 is indicated as well as the summary of the overall staining score index, median + SD

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Cell Communication and Signaling

ISSN: 1478-811X