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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Vitamin D/VDR signaling inhibits LPS-induced IFNγ and IL-1β in Oral epithelia by regulating hypoxia-inducible factor-1α signaling pathway

Fig. 5

VDR depletion promotes HIF-1α levels of mouse oral epithelium in the presence of bacteria. a and b Western blot analyses (a) of oral epithelia lysates in the 4 groups of mice as indicated, and densitometric quantitation of these data (b). c Real-time PCR analyses of transcript levels of IFNγ and IL-1β in mouse oral epithelium. *P < 0.05, **P < 0.01, ***P < 0.001 vs. VDR+/+ controls; #P < 0.05, ##P < 0.01 vs. VDR−/− controls; n = 5. Ctrl, control

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