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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Overexpression of MTA1 inhibits the metastatic ability of ZR-75-30 cells in vitro by promoting MTA2 degradation

Fig. 1

MTA1 overexpression inhibited the metastasis of ZR-75-30 cells. a MTA1 was overexpressed in ZR-75-30-MTA1 stable cell line compared to its control cell line ZR-75-30-Vector. Detected by immunoblot. b Overexpression of MTA1 significantly inhibited the migration and (c) invasion of ZR-75-30 cells in vitro. Detected by transwell migration and invasion assays. 30,000 cells migrated for 24 h. Scale bars = 200 μm, mean ± SD, n = 3,***P < 0.001, **P < 0.01, t test. c MTA1 was overexpressed in MDA-MB-231 cells compared with control cells. d Overexpression of MTA1 significantly promoted the migration and (e) invasion of MDA-MB-231 cells in vitro. Scale bars = 200 μm, mean ± SD, n = 3,***P < 0.001, **P < 0.01, t test

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