Skip to main content
Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

Fig. 6

RHBDD1, p-Akt and CDK2 expression are positively correlated in breast cancer tissues. a The expression of RHBDD1, p-Akt and CDK2 in 84 breast cancer tissue samples were detected by immunohistochemistry. Representative photos showed the consistent expression of RHBDD1, p-Akt and CDK2. Case 1: weak staining; Case 2: moderate staining; Case 3: strong staining. Original magnification, 100×; 400×. b The protein levels of p-Akt and CDK2 were associated with RHBDD1 levels (Pearson’s chi-squared test, p < 0.001). c Boxplots show the consistent expression of RHBDD1, p-Akt and CDK2 in the RHBDD1 weak expression group (white) and the RHBDD1 high expression group (gray) (Wilcoxon rank-sum test, *** p < 0.001)

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X