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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway

Fig. 1

Tumor necrosis factor-a-induced protein 8 elevated expression in clinical NSCLC tissues. a Representative IHC images from a single NSCLC case (T) and the matched adjacent normal lung tissue (N). The protein expression levels of TNFAIP8 were significantly higher in tumour tissues than that in adjacent normal lung tissues. b Histogram showing pooled data derived from NSCLC (T, n = 196) and normal lung (N, n = 50) tissues. High TNFAIP8 expression rate is calculated by dividing the number of patients with high TNFAIP8 expression by the number of all patients. P values were calculated using the χ2 test. c Histogram showing TNFAIP8 mRNA expression in NSCLC (T, n = 20) tissues and adjacent normal lung tissue (N, n = 20). Normalization: The TNFAIP8/actin ratio was first calculated and set as 1.00. d Representative western blot showing TNFAIP8 expression in lung tissues and a histogram showing pooled data from NSCLC (T, n = 20) tissues and adjacent normal lung tissues (N, n = 20). Data are expressed as the mean ± SEM (n = 3). P values were calculated using Student’s t-test

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