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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1

Fig. 2

Correlation between miR-644a and HSF1 expression in HCC cells. (a) Quantitative RT-PCR analysis of miR-644a expression in HCC cell lines, HepG2, SMMC-7721, sk-Hep1, MHCC-97 L, QGY-7701 and the normal liver cells, L-O2. (b) Representative western blot shows HSF1 protein expression in the HCC cell lines HepG2, SMMC-7721, sk-Hep1, MHCC-97 L, and QGY-7701 and the normal liver cells, L-O2. (c) Quantitative RT-PCR analysis of HSF1 mRNA expression in the HCC cell lines, HepG2, SMMC-7721, sk-Hep1, MHCC-97 L, and QGY-7701 and the normal liver cells, L-O2. (d) Spearman’s analysis shows a correlation between miR-644a and HSF1 expression in the HCC cell lines (R2 = 0.522, P < 0.05). Note: Data are represented as the mean ± SD of three independent experiments and were analysed by a paired t-test

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Cell Communication and Signaling

ISSN: 1478-811X