Fig. 4
From: miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT
miR-148b-3p suppressed cell proliferation but had no effect on cell cycle and apoptosis in GIST882 cells. (a) RT-PCR was used to determine the transfection efficiencies of miR-148b-3p mimics or miR-148b-3p inhibitor in the GIST882 cells. (b) CCK8 assay was used to evaluate cell proliferation. (c) The cell cycle status was assessed by flow cytometry. (d) The cell apoptosis was evaluated by Annexin V-FITC/PI staining. P value was calculated by one-way ANOVA. *P<0.05, **P<0.01, NS non-significant