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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Fig. 4

In the presence of adipocytes, accelerated FA trafficking in breast cancer cells was mediated by FABP5. a After ablation of FABP5 using an siRNA kit, cells were harvested 48 h after transfection for western blotting to the validate knockdown effectiveness. b Impact on the proliferative ability of breast cancer cell lines resulting from FABP5knockdown. c Altered migration ability resulting from FABP5 deletion in non-cultivated (NC) and co-cultivated (Coc) cancer cells. d TG storage in breast cancer cells, with FABP5 expressed or ablated, cultivated in the absence or presence of adipocytes. *p < 0.05, **p < 0.01, ****p < 0.0001, “ns” stands for not significant

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