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Table 1 IC50 values of HQGGT in human colon cancer cell lines

From: Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway

Cell line

HQGGT batch #1

HQGGT batch #2

HT-29

1.51 ± 0.22

1.62 ± 0.39

H630

1.11 ± 0.16

1.20 ± 0.36

H630R1

1.33 ± 0.17

1.63 ± 0.55

HCT116

0.78 ± 0.13

0.53 ± 0.28

HCT116 p53(−/−)

0.46 ± 0.07

0.54 ± 0.06

RKO

0.96 ± 0.19

N.D.

SW48

0.31 ± 0.11

N.D.

MC38

0.68 ± 0.25

0.51 ± 0.08

CCD841 (Normal)

1.44 ± 0.23

N.D.

  1. All IC50 values represent the mean ± SD from 3 to 5 independent experiments. N.D Not determined
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Cell Communication and Signaling

ISSN: 1478-811X