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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Crosstalk between glial and glioblastoma cells triggers the “go-or-grow” phenotype of tumor cells

Fig. 2

Proteomic analysis of the secretome of unprimed and primed glial cells. a. Venn diagram showing the total number of proteins identified in primed and unprimed glial cells CM. A higher number of proteins was identified in primed CM (651 proteins) when compared to unprimed (410 proteins), of which 385 were common to both conditions. b. Volcano plot of differential protein secretion in primed and unprimed glial CMs. Significantly differentially secreted proteins are colored in red. c-d. Database for Annotation, Visualization and Integrated Discovery (DAVID) was used to query the secretome of glial cells in order to identify enriched biological terms in the differentially secreted proteins extracted from the MS analysis. Statistically significant enriched GO terms (c) and KEGG pathways (d) are shown. Dashed lines represent p-value = 0.05

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