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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling

Fig. 3

Knockdown of OGN reduces cell proliferation. OGN a mRNA expression at 24 h and b protein expression at 48 h are successfully reduced in OGN cells transfected with OGN siRNA (siOGN) compared with control siRNA (siControl) on qPCR and Western blot analysis, respectively. c Knockdown of OGN reduced cell proliferation as compared to control siRNA transfected cells. d Western blot and densitometry analysis reveals decreased expression of the cell cycle markers cyclin A2 and cyclin B1 at 48 h in cells with knockdown of OGN. *p < 0.05

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