Fig. 6

Key experimental approaches to investigate linear motifs. Best-practice experiments to study short linear motifs can be classified into “general” and “motif type-specific”. We highlight a core set of experiments that have been proven to be useful for investigating short linear motif functionality. See the Additional file 1: Table S1 for the list of experiments used in motif discovery, as extracted from the ELM annotation. PSI-MI terms have been used throughout this diagram wherever possible [78]