Figure 3
From: Syk phosphorylation – a gravisensitive step in macrophage signalling
ROS production is significantly reduced in simulated microgravity when TLR2/6, Dectin-1 and complement receptors are stimulated by non-opsonized zymosan. The influence of simulated microgravity (PMT-Clinostat) on the ROS production of the cell line NR8383 after stimulation with 100 μg/ml non-opsonized zymosan, determined by the oxidation of Luminol (A) and calculated as total ROS production (area under the curve) (B). Normalised data are shown with standard deviation. Significance was estimated by means of Student’s t-test (***p < 0.001).