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Table 1 Correlation of the IHC grading of Brachyury, E-cadherin, Slug and Snail in 43 IgA nephropathy patients

From: The T-box transcription factor Brachyury promotes renal interstitial fibrosis by repressing E-cadherin expression

 

Brachyury IHC results

p-Value*

Negative

Positive

 

Grade 0

Grade 1+

Grade 2+

Grade 3+

 

E-cadherin

Preserved

2

6

7

5

0.047

Loss or reduced

0

3

9

11

Snail IHC results

Negative

Grade 0

0

5

3

2

0.021

 

Grade 1+

2

2

5

3

Positive

Grade 2+

0

2

6

7

 

Grade 3+

0

0

2

4

Slug IHC results

Negative

Grade 0

0

5

2

1

0.031

Grade 1+

1

2

5

3

Positive

Grade 2+

1

2

3

8

Grade 3+

0

0

6

4

  1. *Estimated by χ2 test.