Table 2 Overview of the main used parameters for the core model

Initial number of phagophores

3

Initial size of phagophores

0.06 μm²

Creation rate of phagophores

0.42 min^-1

Mean maturation time of phagophores

7.5 min

Growth rate of phagophores

6e-04 μm² min^-1

Initial number of autophagosomes

31

Growth rate of autophagosomes

8e-05 μm² min^-1

Initial number of lysosomes

19

Initial size of lysosomes

0.095 μm²

Creation rate of lysosomes

1.26 min^-1

Mean life time of lysosomes

18 min

Growth rate of lysosomes

0.002 μm² min^-1

Initial number of autolysosomes

28

Initial size of autolysosomes

0.225 μm²

Mean life time of autolysosomes

95 min

Growth rate of autolysosomes

0.0012 μm² min^-1

Chance of reformation autolysosome to lysosome

50%

Rate of movement

2 μm min^-1

Chance of autophagosomal movement towards nucleus

85%

Chance of lysosomal movement towards nucleus

55%

Chance of fusion between a non-autolysosome and an autolysosome

45%

Chance of fusion between two autolysosomes

15%