Figure 7

Gene expression analysis by qRT-PCR. Expression levels of 15 host genes were measured in the wild type or the itr1aΔ itr3cΔ double mutant-infected mouse brains. Gene expression levels are plotted as relative expression (log2) (average ± SD) in each sample, compared to the levels in the uninfected mice brain. The expression level of each gene was normalized to the levels of endogenous Gapdh in each of the test and control sample. Gene expression was measured three times in each of the three samples per group.