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  • Meeting abstract
  • Open Access

Endocytosis, cell signalling, adhesion and motility

  • 1
Cell Communication and Signaling20097 (Suppl 1) :A101

  • Published:


  • Calcium
  • Growth Factor
  • Cell Migration
  • Cell Signalling
  • Receptor Activation

Endocytosis and exocytosis play a key role in how cells respond to their environment. Endocytosis directly (and indirectly) affects responses to guidance cues and growth factors, the uptake of nutrients and even pathogens; it modulates cell signalling in response to receptor activation and is essential for cell migration. In this talk I will consider the endocytic repertoire of a cell and show how distinct mechanisms may differently affect function. I will describe the characterisation of new endocytic mechanisms and show how a molecular understanding can lead to a better view of function. I will round up with a simple view of how exocytosis can be regulated by calcium mediated signalling.

Authors’ Affiliations

Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, UK


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© McMahon; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.