Table 1 Eps15 binding partners
From: Eps15: a multifunctional adaptor protein regulating intracellular trafficking
Binding partner | Interacting domain | Function | Reference |
|---|---|---|---|
α-adaptin | DPF-motif | Endocytosis | [64] |
γ-adaptin | Domain III | secretion | |
Crk | PRMs | Unknown | [10] |
Eps15/Eps15R | EH domain | Unknown | [46] |
Epsin | EH domain | Endocytosis/nucleus | [51] |
Grb2 | PRMs | Endocytosis | |
Hrb | EH domain | Nucleus/endocytosis | |
Hrs | n.d. | Sorting | [74] |
Intersectin | Coiled-coil domain | Endocytosis | [41] |
Numb | EH domain | Endocytosis | [36] |
Parkin | UIM domains | Mono-ubiquitination | [17] |
POB1 | n.d. | Endocytosis | [79] |
Phocein | n.d. | Trafficking | [80] |
Spartin | n.d. | Endocytosis | [81] |
STAM (EAST) | n.d. | Sorting | [74] |
Stonin2 | EH domain | Endocytosis | [53] |
Synaptojanin | EH domain | Endocytosis | [82] |
Ubiquilin/PLIC | UIM1 | Aggresome formation | [49] |
Ubiquitin | UIM2 | Ubiquitination/unknown |