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Table 2 Effects of DBZ and cisplatin on 8 additional CRC cell lines

From: Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells

CRC line

Val1744-NICD

DBZ 300 nM

Cisplatin cell death (20 μM,48 h)

CP+DBZ combi effect CD (48 h)

COLO 320DM

+ (N)

-

-

-

COLO 741

+ (N)

-

+

+

DLD-1

-

-

(+)

-

HCT 116

+ (N)

-

+

+

RCM-1

+

-

+

(+) (72 h)

RKO

+

-

+

(+) (72 h)

SNU-C2B

+

-

(+)

-

SW620

+

-

+

-

  1. For details on abbreviations see footnote in Table 1
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Cell Communication and Signaling

ISSN: 1478-811X