Table 9 Phosphatases (mouse) that do not have an FXFP motif and/or D-domain sequence. Phosphatases that use phosphatidylinositols or inositols as substrates and do not contain an FXFP or D-domain sequence are listed in the table; all sequences are for mouse proteins. The number of potential MAPK phosphorylation sites and sequences fitting the optimal MAPK phosphorylation in these kinases are also identified.
Isozyme | GenBank Accession # | # amino acids | # (S/T)P sites | Site(s) with the consensus PX(S/T)P sequence |
|---|---|---|---|---|
inositol monophosphatase A2 | NP_444491 | 290 | 1 | none |
inositol monophosphatase A3 | NP_808398 | 356 | 2 | none |
Inositol polyphosphate 1-phosphatase | P49442 | 396 | 2 | none |
Myotubularin; MTM1 | Q9Z2C5 | 603 | 1 | none |
Myotubularin-related protein 2; MTMR2; | Q9Z2D1 (AAH63050) | 643 | 4 | none |
Myotubularin-related protein 3; MTMR3 | CAI35186 | 1159 | 7 | 582PSTP |
Myotubularin-related protein 6; MTMR6 | NP_659092 | 617 | 3 | 555PETP |
Inositol polyphosphate 4-phosphatase, Type Ib (variant) | NP_766559 | 679 | 3 | none |
Inositol 1,4,5-trisphosphate 5-phosphatase, Type I | AAH56341 | 412 | 2 | none |
Synaptojanin 1 (synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) | Q8CHC4 | 1574 | 19 | 1145PPSP 1158PKSP 1443PNSP |
PI(4,5)P2 5-phosphatase A; PIB5PA; PIPP | NP_766027 | 1003 | 31 | 197PQSP 200PSSP 346PRSP |
Skeletal muscle and kidney enriched inositol phosphatase isoform 1; SKIP 1 | Q8C5L6 | 468 | 5 | none |
Phospholipid-inositol phosphatase; PTEN-like phosphatase; PLIP | NP_079852 | 261 | 3 | none |