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Figure 3 | Cell Communication and Signaling

Figure 3

From: Comparable response of ccn1 with ccn2 genes upon arthritis: An in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines

Figure 3

Comparable response of ccn1 and ccn2 to anti-inflammatory dexamethasone in HCS-2/8 cells. A. Expression levels of ccn1 and ccn2 transcripts examined by quantitative real-time PCR. Plotted values represent relative mRNA copy numbers, as described in the legend to Figure 2. Open and solid circles denote ccn1 and ccn2, respectively. B. Control experiments with estrogen, showing no significant alteration in gene expression either in ccn1, or ccn2. These data are mean values of 2 experimental results shown with error bars (SD). C. Northern blot analysis of ccn1 and ccn2 gene expression in HCS-2/8 cells in response to dexamethasone treatment. The ccn1 and ccn2 mRNAs (upper and middle panels) and total RNAs stained with 0.02 % methylene blue (lower panel) are shown. : 28S, 28S ribosomal RNA; 18S, 18S ribosomal RNA.

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Cell Communication and Signaling

ISSN: 1478-811X