Figure 11
From: G-protein-coupled receptor participates in 20-hydroxyecdysone signaling on the plasma membrane
Diagram showing the ErGPCR-mediated nongenomic pathway response to 20E. 20E through ErGPCR nongenomic pathway regulates the cytosolic calcium fast increase, including the release of the intracellular Ca2+, and the influx of the extracellular Ca2+ via T-type calcium channels and TRP channels. 20E also through ErGPCR regulates the rapid phosphorylation and nuclear translocation of Calponin, and through ErGPCR regulates gene transcription in the genomic pathway for metamorphosis.