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Figure 2 | Cell Communication and Signaling

Figure 2

From: Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1

Figure 2

Quantitative real-time PCR for the determination of alterations in gene-expression of selected genes after 4 h. CTGF (A, B), CAV2 (C, D) and ERK1 (E, F) gene expression was analyzed after 4 h exposure of the cells to 2-D Clinostat (A, C, E) or random positioning machine (RPM; B, D, F). CTGF (A, B) was upregulated on both machines while CAV2 (C) and ERK1 (E) were differentially expressed on the CN only. All results are shown as mean ± standard deviation (SD) of n = 10 independent samples, with significance indicated by *P < 0.05 vs. 1g.

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