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Figure 3 | Cell Communication and Signaling

Figure 3

From: AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma

Figure 3

CCL3 increases cell migration through the CCR5 receptor. (A-E): Cells were pretreated for 30 min with CCR5 mAb or Met-RANTES. Subsequently, they were stimulated with CCL3 (30 ng/ml) for 24 h, and in vitro migration (A& B), invasion (C), and MMP-2 (D& E) expression were measured using the Transwell assay, wound healing assay, qPCR, and western blotting. The results are expressed as the mean ± SE. *P < 0.05 compared with control. #P < 0.05 compared with CCL3-treated group.

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Cell Communication and Signaling

ISSN: 1478-811X