Figure 8
From: Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling
Inhibition of mTOR suppresses the hypertrophic effects of PLD1. (A) Myotubes were infected with GFP-adenovirus, or with PLD1-adenovirus, and were subsequently treated or not with 1 μM PP242 for 48 hrs. Myotube area values are means ± SE of n = 10 to 20 fields. (B) CK activity was measured in myotubes treated as above. Results are shown as means ± SE of n = 6 to 12 replicates. ***: different from control, p < 0.0001. NS: no significant difference.