Table 2 Transcript levels of macrophage genes involved in lipid metabolism altered by Mtb infection

Steroyl-CoA desaturase 1

1.85

12.13*

Fatty acid synthesis

Fatty acid desaturase 2

2.95

8.51*

Lipid metabolism

Glycerol-3-phosphate dehydrogenase

1.35

3.61*

Glycerolphospholipid metabolism

Adenosine A2b receptor

1.63

3.59*

Lipid synthesis

Farnesyl diphosphate fanesyltransferase 1

1.53

2.77*

Cholesterol synthesis

Globoside alpha-1,3-N-acetogalatosaminyltransferase 1

1.64

2.75*

Glycolipid metabolism

Acyl-CoA synthetase long chain family member 1

1.71

2.69*

Fatty acid synthesis

Acyl-CoA synthetase short chain family member 1

1.53

2.58*

Lipid synthesis

Hydroxysteroid 17-beta dehydrogenase 7

1.39

2.58

prostaglandin metabolism

Lanosterol synthase 1

1.34

2.51*

Fatty acid metabolism

24-dehydrocholestrol reductase

2.30

2.36*

Cholesterol synthesis

Phosphatidic acid phosphatase type 2B

1.35

2.26*

Lipid synthesis

Acyl-CoA thioesterase 7

1.43

1.82*

Fatty acid metabolism

Steroyl-CoA desaturase 2

1.63

1.80

Fatty acid synthesis

Mevalonate decarboxylase

1.42

1.72*

Cholesterol synthesis

Farnesyl diphosphate synthase

1.30

1.64

Sterol synthesis

Prostaglandin E synthase

1.92

1.60*

Prostaglandin metabolism

Cytochrome P450, family 51, subfamily A, polypeptide 1

1.50

1.35*

Sterol synthesis

Isopentenyl diphosphate delta isomerase 1

1.69

ND

Cholesterol synthesis