CCN5 knock down alters VSMC morphology. Untreated, control siRNA, or CCN5 siRNA treated VSMC were growth arrested by serum starvation for 72 hr. Cells were then placed in serum free RPMI 1640 medium for 48 hours, fixed and stained with Diff-Quik to visualize morphology. A. Untreated B. Control siRNA treated C. CCN5 siRNA treated.