Name | Origin | Molecular weight (kDa) | Composed of: | Conclusion | References |
---|---|---|---|---|---|
Bovicin HC5 | Streptococcus bovis | 2.4 | 22 amino acids | Only at concentrations higher than the concentration required for its biological activity did bovicin HC5 exhibit cytotoxic effects | |
Colicins | E. coli | 40 to 80Â kDa | Colicin Z (151 amino acids) | Modifying the target cell's electric charge distribution (which causes it to die) | |
Nisin A | Lactococcus lactis | 3.3 | 34 amino acids | Through destabilizing cell membranes, inhibiting tumor cell development, pore deformation, changing cell membranes, and increasing ion penetration that tampers with phospholipid organization, it demonstrates its antitumor and anti-metastasis effect | |
Pediocins | Bacterium pediococcus acidilactici MTCC 5101 | 4.6 | 44 amino acids | preventing tumor cells from proliferating by upsetting the cycle of cell division | |
Fermenticin HV6b | Bacterium Lactobacillus fermentum HV6b MTCC 10,770 | 6.7 | –––– | Its ability to induce vascular endothelial cells to undergo apoptosis, break down DNA, and contract cells exhibits its anti-cancer effect | |
S2 Pyocin | Pseudomonas aeruginosa 42A | 73.9 | 777 amino acids | It inhibits the production of lipids in cells and interferes with DNA replication to demonstrate its anti-cancer properties |