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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Exploring the role of Prx II in mitigating endoplasmic reticulum stress and mitochondrial dysfunction in neurodegeneration

Fig. 3

Prx II regulates Armcx3 expression via ERS. (A) Detection of ERS within HT22 cells after alcohol treatment using projection electron microscopy. (B) Western blotting was used to detect PERK signaling pathway protein expression levels. (C) Detection of PERK signaling pathway after 4PBA pretreatment using western blotting. (D) Armcx3 protein expression level after 4PBA pretreatment, assessed using western blotting. (E) Armcx3 expression level after 4PBA pretreatment, assessed using qRT-PCR. (F) Ca2+ level in the mitochondria after 4PBA pretreatment, assessed using flow cytometry. (G) Quantitative analysis of the data in panel “f.” (H) Mitochondrial membrane potential after 4PBA pretreatment, assessed using fluorography. Each analysis was performed in triplicate

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Cell Communication and Signaling

ISSN: 1478-811X