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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Exploring the role of Prx II in mitigating endoplasmic reticulum stress and mitochondrial dysfunction in neurodegeneration

Fig. 2

Prx II regulates Armcx3 mitochondrial subcellular localization to regulate EMCS formation. (A) Confocal microscopy was used to detect mitochondrial subcellular localization. (B) RNA-seq analysis of GO of mock HT22 and shPrx II HT22 cells involved in mitochondrial subcellular localization after alcohol treatment. (C) RNA-seq analysis of differentially expressed genes involved in the mitochondrial subcellular localization of mock HT22 and shPrx II HT22 cells after alcohol treatment and plotting heat map; red and blue indicate upregulated and downregulated genes, respectively. (D) Armcx3 mRNA expression levels were verified using qRT-PCR. (E) Western blotting was used to detect Armcx3 protein expression levels. Each analysis was performed in triplicate

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Cell Communication and Signaling

ISSN: 1478-811X