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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway

Fig. 5

BMP2 as the core prognostic VMRG for LSCC progression. A KM curve based on VM scores in LSCC. B Differentially expressed genes in high-and low-VM score groups. C–D LASSO and SVM-RFE screening of candidate diagnostic genes. E WGCNA of differentially expressed genes. F Correlations of VM scores with WGCNA modules. G Correlation between the blue module and VM scores. H Five algorithmic Venn diagram screening genes. I–J The AUC of BMP2 and TWIST1. K Heatmap of gene correlation analysis. L Differences in the expression of two core genes between high- and low-VM score groups. M–N Differential expression of two core genes between normal and tumor samples. O–P KM survival analysis of BMP2 and TWIST1 in LSCC. Q ROC curves of survival. R Differential expression of two core genes in GSE51985 data

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Cell Communication and Signaling

ISSN: 1478-811X