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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Interleukin-4 protects retinal ganglion cells and promotes axon regeneration

Fig. 7

rIL-4 treatment improves ERG performance in mice with NMDA-induced retina injury. A: Representative PhNR waveforms from eyes in blank control group, vehicle group and rIL-4 group, after 7-day NMDA damage. The PhNR was elicited with flash stimulus at an intensity of 10.0 cd·s/m2 and measured from the baseline to the bottom of the trough following the b wave. B: Average amplitudes of PhNR in each group. C: Representative pSTR waveforms in each group. The pSTR was elicited with a flash stimulus at an intensity of 0.001 cd·s/m2 and measured from the baseline to the following positive peak of the waveform. D: Average amplitudes of pSTR in each group. E: Representative OP waveforms in each group. The OPs were elicited with the white flashes of 3.0 cd·s/m2 and recorded via bandpass filtering between 50 and 170 Hz. F: Average amplitudes of OPs (OP1, OP2, and OP3) in each group. G: Representative scotopic ERG responses in response to the increasing flash intensity in each group. The flash intensities used to elicit the responses are presented to the left. H: Average amplitudes of a- and b- waves in scotopic ERG responses, respectively. n = 4 eyes per group, * indicates p < 0.05, ** indicates p < 0.01, *** indicates p < 0.005

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