Protein | Control | SC | Colchicine | SC + Colchicine | p-value |
---|---|---|---|---|---|
KU70 | 1.00 ± 0.05 | 1.16 ± 0.00 | 1.01 ± 0.02 | 1.00 ± 0.02 | 0.0003 |
KU80 | 1.00 ± 0.09 | 1.19 ± 0.09 | 1.05 ± 0.03 | 1.04 ± 0.01 | 0.0382 |
Lamin B1 | 1.00 ± 0.14 | 0.76 ± 0.00 | 1.06 ± 0.05 | 1.09 ± 0.09 | 0.0046 |
P53 | 1.00 ± 0.21 | 2.03 ± 0.13 | 1.06 ± 0.28 | 0.75 ± 0.39 | 0.0019 |
P21 | 1.00 ± 0.10 | 1.86 ± 0.35 | 1.45 ± 0.09 | 0.70 ± 0.22 | 0.0009 |
MMP-2 | 1.00 ± 0.05 | 1.60 ± 0.02 | 1.37 ± 0.15 | 1.20 ± 0.11 | 0.0004 |
P65 | 1.00 ± 0.08 | 1.00 ± 0.05 | 0.96 ± 0.03 | 0.93 ± 0.00 | 0.2722 |
p-P65 | 1.00 ± 0.09 | 1.51 ± 0.09 | 0.91 ± 0.03 | 1.11 ± 0.01 | 0.0001 |
p-65/P65 | 1.00 ± 0.05 | 1.51 ± 0.05 | 0.96 ± 0.06 | 1.20 ± 0.01 | 0.0001 |
p-P38 | 1.00 ± 0.14 | 5.76 ± 0.29 | 0.94 ± 0.02 | 1.03 ± 0.06 | 0.0001 |
p-ERK | 1.00 ± 0.04 | 1.90 ± 0.24 | 1.08 ± 0.10 | 0.72 ± 0.08 | 0.0001 |
p-JNK | 100 ± 0.18 | 1.08 ± 0.14 | 0.95 ± 0.12 | 1.10 ± 0.05 | 0.5054 |
p-mTOR | 1.00 ± 0.18 | 1.21 ± 0.11 | 1.18 ± 0.11 | 1.06 ± 0.14 | 0.2772 |
p-S6 | 1.00 ± 0.03 | 1.69 ± 0.03 | 1.52 ± 0.03 | 1.22 ± 0.09 | 0.0001 |
p-4EBP1 | 1.00 ± 0.10 | 0.94 ± 0.24 | 1.40 ± 0.04 | 1.52 ± 0.19 | 0.0057 |