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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Tobacco smoke condensate-induced senescence in endothelial cells was ameliorated by colchicine treatment via suppression of NF-κB and MAPKs P38 and ERK pathways activation

Fig. 2

Colchicine inhibited smoke condensate-induced senescence in endothelial cells. (A) SA-β-gal staining and (B) IF staining for Lamin B1 in endothelial cells treated with different conditions for 24 h. The quantification of (C) SA-β-gal staining and (D) Lamin B1 IF staining. (E) WB showing protein expression of Lamin B1, P53, and P21. The relative protein expression of (F) Lamin B1, (G) P53, and (H) P21. (I) The relative mRNA expression of P21. The experiments were performed with biological triplicates. β-actin was used as a control. SC (smoke condensate). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, scale bar = 100 μm

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Cell Communication and Signaling

ISSN: 1478-811X