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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Repetitive transcranial magnetic stimulation ameliorates cognitive deficits in mice with radiation-induced brain injury by attenuating microglial pyroptosis and promoting neurogenesis via BDNF pathway

Fig. 7

Inhibiting BDNF pathway reversed the enhancement of synaptic plasticity after rTMS treatment. (A-C) The protein levels of PSD95 and Synaptophysin, n = 3 for each group. (D) Representative images of Golgi staining and tertiary dendritic profile of granule cells in DG region of hippocampus. Scale bar = 200 μm for images of hippocampus; and scale bar = 10 μm for tertiary dendritic images. (E) The spines density of tertiary dendritic per horizons. n = 2 for each group and 6 horizons were randomly chosen for analysis. All data are presented as mean ± SEM, *P < 0.05, **P < 0.01 vs. Sham group; #P < 0.05, ##P < 0.01 vs. Radiation group; &P < 0.05, &&P < 0.01 vs. rTMS group

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