Skip to main content
Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Repetitive transcranial magnetic stimulation ameliorates cognitive deficits in mice with radiation-induced brain injury by attenuating microglial pyroptosis and promoting neurogenesis via BDNF pathway

Fig. 5

Inhibiting BDNF pathway attenuated the level of hippocampal neurogenesis after rTMS treatment. (A) Representative images of immunofluorescence staining of DCX (green)/BrdU (red) in hippocampal sections from Sham and cranial irradiation mice treated with rTMS and K252a. Scale bar = 100 μm. (B) Integrated density of DCX in DG region of hippocampus. (C) The number of DCX/BrdU positive cells in DG. (D) Representative images immunofluorescence staining of NeuN (green)/BrdU (red) in hippocampal sections. Scale bar = 100 μm. (E) The number of NeuN/BrdU positive cells in DG of hippocampus. All data are presented as mean ± S.E.M, n = 3 for each group. *P < 0.05, **P < 0.01 vs. Sham group; ##P < 0.01 vs. Radiation group; &P < 0.05, &&P < 0.01 vs. rTMS group; ns. no significance

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X