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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: Single cell analysis reveals the roles and regulatory mechanisms of type-I interferons in Parkinson’s disease

Fig. 9

A-C ELISA results indicate that NFATc2 regulates the release of proinflammatory cytokines IL-1β (A), IL-6 (B), and TNF-α (C) in MPP+-induced BV-2 cells. D-E NFATc2 regulates the levels of IFN-β rather than IFN-α. F Knocking down NFATc2 can alleviate apoptosis in SH-SY5Y cells co-cultured in conditioned medium. G-L Western blot and the corresponding statistical analysis for NFATc2 (H), p-p65/ p65 (I), p-IκBα/IκBα(J), IRF9 (K), and p-STAT1/STAT1(L)

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Cell Communication and Signaling

ISSN: 1478-811X