Cell Communication and Signaling

Table 1 The mechanism of STING works in the treatment of NSCLC

From: Role of STING in the treatment of non-small cell lung cancer

Therapy	Medicine	Mechanism	Reference
Chemotherapy	Carboplatin	STING-TBK1-IRF3	[100]
		STING-NF-κB	[100]
	Cisplatin	STING-TANK-TBK1-IRF3	[102]
		STING-ATM-IFI16-NF-κB	[102]
	PEM	STING-TANK-TBK1-IRF3	[102]
		STING-ATM-IFI16-NF-κB	[102]
		STING-TBK3-IRF1-STAT73	[79]
RT	/	cGAS-STING	[45]
MTT	Anlotinib	cGAS-STING-IRF3	[104]
	Osimertinib	cGAS-STING	[105]
NT	MDPMH	cGAS-STING	[117]
	Bio-MnO2 NPs	cGAS-STING	[118]
	IO-PG-GLU-Ce6	cGAS-STING	[119]

Abbreviations: PEM pemetrexed, RT radiotherapy, MTT molecular targeted therapy, NT nano-technology, MDPMH Mn-modified phthalocyanine derivative @ docetaxel @ PLGA @ Mn2⁺ @ HA, Bio-MnO2 NPs biomineralized manganese oxide nanoparticles, IO-PG-GLU-Ce6 iron oxide-polyglycerol-glucose-chlorin e6

Back to article page

ISSN: 1478-811X

Contact us

General enquiries: journalsubmissions@springernature.com