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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: The protein composition of exosomes released by prostate cancer cells is distinctly regulated by androgen receptor-antagonists and -agonist to stimulate growth of target cells

Fig. 5

Pathway analysis of 138 common exosomal proteins suggest activation of pro-proliferative pathways. A Highest enriched pathways according to the detected 138 common exosomal proteins between SAL and Enz. X-axis represents the fold enrichment of the expressed proteins enriched in the indicated pathway. Size of the dots indicates the number of significant proteins in the given enriched pathway. Color indicates -log10 (lowest p-value). B Network visualizes which proteins are involved in the enriched pathway and how the proteins are connected in different pathways. Pathways in the network are shown according to the reactome ID number. C UpSet Plot shows a matrix of enriched pathways and the number of proteins at the corresponding intersections of enriched pathways. (n = 4)

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Cell Communication and Signaling

ISSN: 1478-811X